New treatment for breast cancer in sight?

New treatment for breast cancer in sight? -Times of IndiaYou are here: Home > collections >cellsnew treatment for breast cancer in sight?IS Ian's January 16, 2014, 12:00tags: women|Harvard-University|founding-Director|breast cancer therapy|Amy Brock(new treatment of breast cancer,...)

More women undergo now early tests to reveal the precancerous breast tissue.

Early diagnosis can save lives, but in reality few of these lesions cause tumors -, and doctors have no good way to predict who will.

As a result, many women are operated, which might never develop the disease.

All that may change soon.

Researchers of the Wyss Institute for biologically inspired engineering at Harvard University have discovered a new breast cancer treatment, the partial returns the cancer condition in cultured breast cancer cells and prevents the development of cancer in mice.

This could pave to handle the way for the early stages of the disease without resorting to surgery, chemotherapy and radiotherapy, says a new study, published in the journal Science translational medicine.

"The findings open the possibility of someday treat patients who could alleviate a genetic propensity for cancer, to change people's lives and too much fear," said Don Ingber, founding Director, Wyss Institute.

Amy Brock, former Wyss Institute postdoctoral fellow, grew healthy mouse or human cells of the mammary gland in a nutrient-rich, tissue-friendly gel.

Healthy cells ensconced in the gel formed hollow balls cells similar to a normal milk channel. But cancer cells, unlike in tumor-like solid, packed balls together.

Brock RNA treated these cancer cells with a short piece of a small interference RNA (SiRNA) this block known only the HoxA1 gene, according to the study.

The cells reverse stop their March to hypercalcemia, their runaway growth and form hollow balls, such as the healthy cells. What's more, as if they were growing in healthy tissue specialized.

The SiRNA treatment stopped in a line of mice that are genetically modified to have a gene that causes all of them cancer of breast that develop cancer.

"There was no aha moment. But after enough builds evidence, consult each other and say this really hurt, "added Brock.

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